In mammals,
hyaluronan is widely distributed throughout the body where it is a
major
component of the connective tissues. Its purpose is to provide
structure
and stability to the tissues and to form a fluid matrix in which
collagen
and elastin fibres are embedded.
Hyaluronan is metabolised quickly in the body, so it was necessary
to develop
a derivative of this that has a slower degradation time.
By cross linking
the hyaluronan, Hylan B gel, the active component of Hylaform, was
created.
Hylan B gel restores a hydrated elastic feel when implanted into the
dermal
tissue because of its water attracting capacity.
Hylaform
is injected beneath the skin to plump out lines and wrinkles.
It is important to inject exactly the right amount of Hylaform
because
if there is too little the product does not last, and if there
is too
much it can be forced out of position or cause inflammation in
surrounding
tissues. Therefore it may be necessary to fill defects
in stages, with
top up treatments being done after the initial treatment
at approximately
fortnightly intervals until the desired result
is achieved.
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The
amount of Hylaform required to correct a
person's lines and wrinkles
will depend on the depth of the wrinkles, their
cause, and the amount
of muscle movement to which the area is subjected.
Hylaform
is better suited to deep or coarse lines, and is not the
product
of choice for fine or superficial lines.
It
is not generally suitable in the upper face, but
is particularly
good for lip augmentation and filling of
nasolabial and marionette
furrows.
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